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PUBLISHED WORK

The Fruits of Our Labour

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2020 PUBLICATIONS

Recent publications

EBF1-CORRELATED LONG NON-CODING RNA TRANSCRIPT LEVELS IN 3RD TRIMESTER MATERNAL BLOOD AND RISK OF SPONTANEOUS PRETERM BIRTH. 

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Zhou G, Holzman C, Chen B, Wang P, Heng YJ, Kibschull M, Lye SJ, Kasten EP.Reprod Sci. 2020 Sep 21. doi: 10.1007/s43032-020-00320-5. Online ahead of print.PMID: 32959224

PALMITIC ACID INDUCES INFLAMMATION IN PLACENTAL TROPHOBLASTS AND IMPAIRS THEIR MIGRATION TOWARD SMOOTH MUSCLE CELLS THROUGH PLASMINOGEN ACTIVATOR INHIBITOR-1.

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Rampersaud AM, Dunk CE, Lye SJ, Renaud SJ.Mol Hum Reprod. 2020 Nov 1;26(11):850-865. doi: 10.1093/molehr/gaaa061.PMID: 32898274

EXPRESSION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 CELL ENTRY GENES, ANGIOTENSIN-CONVERTING ENZYME 2 AND TRANSMEMBRANE PROTEASE SERINE 2, IN THE PLACENTA ACROSS GESTATION AND AT THE MATERNAL-FETAL INTERFACE IN PREGNANCIES COMPLICATED BY PRETERM BIRTH OR PREECLAMPSIA.

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Bloise E, Zhang J, Nakpu J, Hamada H, Dunk CE, Li S, Imperio GE, Nadeem L, Kibschull M, Lye P, Matthews SG, Lye SJ.Am J Obstet Gynecol. 2020 Aug 25:S0002-9378(20)30884-X. doi: 10.1016/j.ajog.2020.08.055. Online ahead of print.PMID: 32853537 

DIFFERENTIAL ROLE OF SMAD2 AND SMAD3 IN THE ACQUISITION OF AN ENDOVASCULAR TROPHOBLAST-LIKE PHENOTYPE AND PREECLAMPSIA.

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Brkić J, Dunk C, Shan Y, O'Brien JA, Lye P, Qayyum S, Yang P, Matthews SG, Lye SJ, Peng C.Front Endocrinol (Lausanne). 2020 Jul 8;11:436. doi: 10.3389/fendo.2020.00436. eCollection 2020.PMID: 32733385 

EFFECTS OF THE GLOBAL CORONAVIRUS DISEASE-2019 PANDEMIC ON EARLY CHILDHOOD DEVELOPMENT: SHORT- AND LONG-TERM RISKS AND MITIGATING PROGRAM AND POLICY ACTIONS.

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Yoshikawa H, Wuermli AJ, Britto PR, Dreyer B, Leckman JF, Lye SJ, Ponguta LA, Richter LM, Stein A.J Pediatr. 2020 Aug;223:188-193. doi: 10.1016/j.jpeds.2020.05.020. Epub 2020 May 19.PMID: 32439312 

DECIPHERING A DISTINCT REGULATORY NETWORK OF TEAD4, CDX2 AND GATA3 IN HUMANS FOR TROPHOBLAST TRANSITION FROM EMBRYONIC STEM CELLS.

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Xiao L, Ma L, Wang Z, Yu Y, Lye SJ, Shan Y, Wei Y.Biochim Biophys Acta Mol Cell Res. 2020 Sep;1867(9):118736. doi: 10.1016/j.bbamcr.2020.118736. Epub 2020 May 7.PMID: 32389642

COMBINATORIAL EXTRACELLULAR MATRIX MICROARRAY IDENTIFIES NOVEL BIOENGINEERED SUBSTRATES FOR XENO-FREE CULTURE OF HUMAN PLURIPOTENT STEM CELLS.

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Ireland RG, Kibschull M, Audet J, Ezzo M, Hinz B, Lye SJ, Simmons CA.Biomaterials. 2020 Jul;248:120017. doi: 10.1016/j.biomaterials.2020.120017. Epub 2020 Apr 3.PMID: 32283392

MATERNAL BLOOD EBF1-BASED MICRORNA TRANSCRIPTS AS BIOMARKERS FOR DETECTING RISK OF SPONTANEOUS PRETERM BIRTH: A NESTED CASE-CONTROL STUDY.

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Zhou G, Holzman C, Heng YJ, Kibschull M, Lye SJ.J Matern Fetal Neonatal Med. 2020 Apr 1:1-9. doi: 10.1080/14767058.2020.1745178. Online ahead of print.PMID: 32237936

LOW MOLECULAR WEIGHT HEPARIN PROMOTES TRANSCRIPTION AND RELEASE OF PLACENTAL GROWTH FACTOR FROM ENDOTHELIAL CELLS.

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McLaughlin K, Nadeem L, Wat J, Baczyk D, Lye SJ, Kingdom JC.Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H1008-H1017. doi: 10.1152/ajpheart.00109.2020. Epub 2020 Mar 20.PMID: 32196359

EBF1 GENE MRNA LEVELS IN MATERNAL BLOOD AND SPONTANEOUS PRETERM BIRTH.

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Zhou G, Holzman C, Heng YJ, Kibschull M, Lye SJ, Vazquez A.Reprod Sci. 2020 Jan;27(1):316-324. doi: 10.1007/s43032-019-00027-2. Epub 2020 Jan 1.PMID: 32046385

MATERNAL MALNUTRITION IMPACTS PLACENTAL MORPHOLOGY AND TRANSPORTER EXPRESSION: AN ORIGIN FOR POOR OFFSPRING GROWTH.

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Connor KL, Kibschull M, Matysiak-Zablocki E, Nguyen TTN, Matthews SG, Lye SJ, Bloise E.J Nutr Biochem. 2020 Apr;78:108329. doi: 10.1016/j.jnutbio.2019.108329. Epub 2020 Jan 8.PMID: 32004932

ASSOCIATION BETWEEN MATERNAL ACETAMINOPHEN USE AND ADVERSE BIRTH OUTCOMES IN A PREGNANCY AND BIRTH COHORT.

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Arneja J, Hung RJ, Seeto RA, Knight JA, Hewko SL, Bocking A, Lye SJ, Brooks JD.Pediatr Res. 2020 Jun;87(7):1263-1269. doi: 10.1038/s41390-019-0726-8. Epub 2019 Dec 18.

2019 PUBLICATIONS

Recent publications

INTERACTION OF PREGNANCY-SPECIFIC GLYCOPROTEIN 1 WITH INTEGRIN Α5Β1 IS A MODULATOR OF EXTRAVILLOUS TROPHOBLAST FUNCTIONS.

Cells. 2019 Oct 31;8(11). pii: E1369. doi: 10.3390/cells8111369.

Rattila S, Dunk CEE, Im M, Grichenko O, Zhou Y, Yanez-Mo M, Blois SM, Yamada KM, Erez O, Gomez-Lopez N, Lye SJ, Hinz B, Romero R, Cohen M, Dveksler G

BREAST CANCER RESISTANCE PROTEIN (BCRP/ABCG2) INHIBITS EXTRA VILLOUS TROPHOBLAST MIGRATION: THE IMPACT OF BACTERIAL AND VIRAL INFECTION

Lye P, Bloise E, Nadeem L, Peng C, Gibb W, Ortiga-Carvalho TM, Lye SJ, Matthews SG.

Cells. 2019 Sep 26;8(10). pii: E1150. doi: 10.3390/cells8101150.

MICRORNA-TRANSCRIPTOME NETWORKS IN WHOLE BLOOD AND MONOCYTES OF WOMEN UNDERGOING PRETERM LABOUR.

Paquette AG, Shynlova O, Wu X, Kibschull M, Wang K, Price ND, Lye SJ.

J Cell Mol Med. 2019 Oct;23(10):6835-6845. doi: 10.1111/jcmm.14567. Epub 2019 Jul 24.

UTERINE ARTERY AND UMBILICAL VEIN BLOOD FLOW ARE UNAFFECTED BY MODERATE HABITUAL PHYSICAL ACTIVITY DURING PREGNANCY.

Sussman D, Saini BS, Schneiderman JE, Spitzer R, Seed M, Lye SJ, Wells GD.

Prenat Diagn. 2019 Oct;39(11):976-985. doi: 10.1002/pd.5517. Epub 2019 Jul 29.

ENVIRONMENTAL, SOCIAL, AND STRUCTURAL CONSTRAINTS FOR HEALTH BEHAVIOR: PERCEPTIONS OF YOUNG URBAN BLACK WOMEN DURING THE PRECONCEPTION PERIOD-A HEALTHY LIFE TRAJECTORIES INITIATIVE.

Ware LJ, Prioreschi A, Bosire E, Cohen E, Draper CE, Lye SJ, Norris SA.

J Nutr Educ Behav. 2019 Sep;51(8):946-957. doi: 10.1016/j.jneb.2019.04.009. Epub 2019 May 15.

URBAN YOUNG WOMEN'S PREFERENCES FOR INTERVENTION STRATEGIES TO PROMOTE PHYSICAL AND MENTAL HEALTH PRECONCEPTION: A HEALTHY LIFE TRAJECTORIES INITIATIVE (HELTI).

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Draper CE, Bosire E, Prioreschi A, Ware LJ, Cohen E, Lye SJ, Norris SA.

Prev Med Rep. 2019 Mar 15;14:100846. doi: 10.1016/j.pmedr.2019.100846. eCollection 2019 Jun.

FAILURE OF DECIDUALIZATION AND MATERNAL IMMUNE TOLERANCE UNDERLIES UTEROVASCULAR RESISTANCE IN INTRA UTERINE GROWTH RESTRICTION.

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Dunk C, Kwan M, Hazan A, Walker S, Wright JK, Harris LK, Jones RL, Keating S, Kingdom JCP, Whittle W, Maxwell C, Lye SJ.

TGFB1 SUPPRESSES THE ACTIVATION OF DISTINCT DNK SUBPOPULATIONS IN PREECLAMPSIA.

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Zhang J, Dunk CE, Shynlova O, Caniggia I, Lye SJ.

EBioMedicine. 2019 Jan;39:531-539. doi: 10.1016/j.ebiom.2018.12.015. Epub 2018 Dec 19.

GESTATIONAL AGE-DEPENDENT GENE EXPRESSION PROFILING OF ATP-BINDING CASSETTE TRANSPORTERS IN THE HEALTHY HUMAN PLACENTA.

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Imperio GE, Javam M, Lye P, Constantinof A, Dunk CE, Reis FM, Lye SJ, Gibb W, Matthews SG, Ortiga-Carvalho TM, Bloise E.

DECIDUAL LEUCOCYTES INFILTRATING HUMAN SPIRAL ARTERIOLES ARE RICH SOURCE OF MATRIX METALLOPROTEINASES AND DEGRADE EXTRACELLULAR MATRIX IN VITRO AND IN SITU.

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Choudhury RH, Dunk CE, Lye SJ, Harris LK, Aplin JD, Jones RL.

Am J Reprod Immunol. 2019 Jan;81(1):e13054. doi: 10.1111/aji.13054. Epub 2018 Sep 29.

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