Deprest JA, Cartwright R, Dietz HP, Brito LGO, Koch M, Allen-Brady K, Manonai J, Weintraub AY, Chua JWF, Cuffolo R, Sorrentino F, Cattani L, Decoene J, Page AS, Weeg N, Varella Pereira GM, Mori da Cunha de Carvalho MGMC, Mackova K, Hympanova LH, Moalli P, Shynlova O, Alperin M, Bortolini MAT

The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Shynlova O, Nadeem L, Dorogin A, Mesiano S, Lye S

Age and/or postmenopausal status as risk factors for pelvic organ prolapse development: systematic preview with meta-analysis

Brito LGO, Pereira GMV, Moalli P, Shynlova O, Manonai J, Weintraub AY, Deprest J, Bortolini MAT

Foundational science and mechanistic insights for a shared disease model: an expert consensus

Alperin M, Abramowitch S, Alarab M, Bortolini M, Brown B, Burnett LA, Connell KA, Damaser MS, de Vita R, Gargett CE, Guess MK, Guler Z, Jorge RN, Kelley RS, Kibschull M, Miller K, Moalli PA, Mysorekar IU, Routzong MR, Shynlova O, Swenson CW, Therriault MA, Northington GM

Foundational science and mechanistic insights for a shared disease model: an expert consensus : developed by the AUGS Basic Science Subcommittee and IUGA Special Interest Group

Alperin M, Abramowitch S, Alarab M, Bortolini M, Brown B, Burnett LA, Connell KA, Damaser M, de Vita R, Gargett CE, Guess MK, Guler Z, Jorge RN, Kelley RS, Kibschull M, Miller K, Moalli PA, Mysorekar IU, Routzong MR, Shynlova O, Swenson CW, Therriault MA, Northington GM

2021 PUBLICATIONS

A broad-spectrum chemokine inhibitor blocks inflammation-included myometrial myocyte-macrophage crosstalk and myometrial contraction

Boros-Rausch A, Shynlova O, Lye SJ

Decidual inflammation drives chemokine-mediated immune infiltration contributing to term labor

Shynlova O, Boros-Rausch A, Farine T, Adams-Wardorf KM, Dunk C, Lye S

Landscape of preterm birth therapeutics and a path foward

Coler BS, Shynlova O, Boros-Rausch A, Lye S, McCartney S, Leimert KB, Xu W, Chemtob S, Olson D, Li M, Huebner E, Curtin A, Kachikis A, Savitsky L, Paul JW, Smith R, Adams Waldorf KM

Pro-inflammatory signals induce 20 α-HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal

Nadeem L, Balendran R, Dorogin A, Mesiano S, Shynlova O, Lye S

Transcriptional control of parturition: insights from gene regulation studies in the myometrium

Khader N, Shchuka V, Shynlova O, Mitchell J

Combination of histochemical analyses and micro-MRI regional changes of the murine cervix in preparation for labor

Chatterjee A, Saghain R, Dorogin A, Cahill L, Sled J, Lye S, Shynlova O

Low-intensity physical activity may protect pregnant women against spontaneous preterm labour: a prospective case-control study

Steckle V, Shynlova O, Lye S, Bocking A

2020 PUBLICATIONS

The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice

Shchuka V, Abatti L, Hou H, Dorogin A, Wilson M, Shynlova O, Mitchell J

Myometrial activation: Novel concepts underlying labor

Shynlova O, Nadeem L, Zhang J, Dunk C, and Lye S

A broad spectrum chemokine inhibitor prevents preterm labor but not microbial invasion of the amniotic cavity or neonatal morbidity in a non-human primate model

Coleman M, Orvis A, Wu T-Y, Dacanay M, Merillat S, Ogle J, Baldessari A, Kretzer N, Munson J, Boros-Rausch A, Shynlova O, Lye S, Rajagopal L, Adams Waldorf KM